Synaptopodin 2-like protein (SYNPO2L)
Homo sapiens — UniProt Q9H987
Data last refreshed: (UniProt release unknown)
Key facts
Synaptopodin 2-like protein (SYNPO2L) is a protein from Homo sapiens identified by UniProt accession Q9H987, 977 residues long. MolForge cross-references it against 0 known binders and 26 disease associations.
- UniProt accession: Q9H987; gene symbol SYNPO2L.
- Organism: Homo sapiens.
- Length: 977 amino acids.
- Top disease associations (Open Targets): electrocardiography, atrial fibrillation and systolic blood pressure.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Synaptopodin 2-like protein |
|---|---|
| UniProt accession | Q9H987 |
| Gene | SYNPO2L |
| Organism | Homo sapiens |
| Length | 977 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (26)
Diseases linked to this target (Open Targets).
- electrocardiography · score 0.42
- atrial fibrillation · score 0.41
- systolic blood pressure · score 0.35
- diastolic blood pressure · score 0.31
- heart failure · score 0.25
- pulse pressure measurement · score 0.25
- eosinophil count · score 0.22
- hypertrophic cardiomyopathy · score 0.22
- chronic obstructive pulmonary disease · score 0.18
- resting heart rate · score 0.18
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H987-F1 | alphafold | PREDICTED | 52.43 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H987.
Amino-acid sequence (977 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SYNPO2L?
The strongest Open Targets associations for SYNPO2L are electrocardiography, atrial fibrillation, systolic blood pressure, diastolic blood pressure and heart failure.
How long is the SYNPO2L protein?
The Homo sapiens SYNPO2L protein (UniProt Q9H987) is 977 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H987 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H987 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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