CCR4-NOT transcription complex subunit 10 (CNOT10)
Homo sapiens — UniProt Q9H9A5
Data last refreshed: (UniProt release unknown)
Key facts
CCR4-NOT transcription complex subunit 10 (CNOT10) is a protein from Homo sapiens identified by UniProt accession Q9H9A5, 744 residues long. MolForge cross-references it against 0 known binders and 21 disease associations.
- UniProt accession: Q9H9A5; gene symbol CNOT10.
- Organism: Homo sapiens.
- Length: 744 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, low grade glioma and head and neck squamous cell carcinoma.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | CCR4-NOT transcription complex subunit 10 |
|---|---|
| UniProt accession | Q9H9A5 |
| Gene | CNOT10 |
| Organism | Homo sapiens |
| Length | 744 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (21)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.54
- low grade glioma · score 0.25
- head and neck squamous cell carcinoma · score 0.23
- endometrial cancer · score 0.23
- gastric adenocarcinoma · score 0.23
- urinary bladder cancer · score 0.23
- lung adenocarcinoma · score 0.23
- prostate adenocarcinoma · score 0.14
- attention deficit hyperactivity disorder · score 0.06
- asthma · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H9A5-F1 | alphafold | PREDICTED | 79.25 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H9A5.
Amino-acid sequence (744 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with CNOT10?
The strongest Open Targets associations for CNOT10 are neurodegenerative disease, low grade glioma, head and neck squamous cell carcinoma, endometrial cancer and gastric adenocarcinoma.
How long is the CNOT10 protein?
The Homo sapiens CNOT10 protein (UniProt Q9H9A5) is 744 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H9A5 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H9A5 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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