Leucine-rich repeat-containing protein 40 (LRRC40)
Homo sapiens — UniProt Q9H9A6
Data last refreshed: (UniProt release unknown)
Key facts
Leucine-rich repeat-containing protein 40 (LRRC40) is a protein from Homo sapiens identified by UniProt accession Q9H9A6, 602 residues long. MolForge cross-references it against 0 known binders and 13 disease associations.
- UniProt accession: Q9H9A6; gene symbol LRRC40.
- Organism: Homo sapiens.
- Length: 602 amino acids.
- Top disease associations (Open Targets): mathematical ability, cognitive function measurement and self reported educational attainment.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Leucine-rich repeat-containing protein 40 |
|---|---|
| UniProt accession | Q9H9A6 |
| Gene | LRRC40 |
| Organism | Homo sapiens |
| Length | 602 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (13)
Diseases linked to this target (Open Targets).
- mathematical ability · score 0.11
- cognitive function measurement · score 0.11
- self reported educational attainment · score 0.11
- adolescent idiopathic scoliosis · score 0.06
- hypertension · score 0.02
- chronic kidney disease · score 0.01
- acute quadriplegic myopathy · score 0.00
- disorder of glycogen metabolism · score 0.00
- Parkinson disease · score 0.00
- Sepsis · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H9A6-F1 | alphafold | PREDICTED | 82.87 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H9A6.
Amino-acid sequence (602 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with LRRC40?
The strongest Open Targets associations for LRRC40 are mathematical ability, cognitive function measurement, self reported educational attainment, adolescent idiopathic scoliosis and hypertension.
How long is the LRRC40 protein?
The Homo sapiens LRRC40 protein (UniProt Q9H9A6) is 602 amino acids long.
Browse: Targets: L · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H9A6 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H9A6 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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