RecQ-mediated genome instability protein 1 (RMI1)
Homo sapiens — UniProt Q9H9A7
Data last refreshed: (UniProt release unknown)
Key facts
RecQ-mediated genome instability protein 1 (RMI1) is a protein from Homo sapiens identified by UniProt accession Q9H9A7, 625 residues long. MolForge cross-references it against 0 known binders and 99 disease associations.
- UniProt accession: Q9H9A7; gene symbol RMI1.
- Organism: Homo sapiens.
- Length: 625 amino acids.
- Top disease associations (Open Targets): cancer, lymphocyte count and sex hormone-binding globulin measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | RecQ-mediated genome instability protein 1 |
|---|---|
| UniProt accession | Q9H9A7 |
| Gene | RMI1 |
| Organism | Homo sapiens |
| Length | 625 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (99)
Diseases linked to this target (Open Targets).
- cancer · score 0.53
- lymphocyte count · score 0.34
- sex hormone-binding globulin measurement · score 0.31
- age at menarche · score 0.31
- total blood protein measurement · score 0.31
- smoking initiation · score 0.31
- smoking status measurement · score 0.30
- body fat distribution · score 0.29
- body height · score 0.29
- breast adenocarcinoma · score 0.28
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H9A7-F1 | alphafold | PREDICTED | 67.52 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H9A7.
Amino-acid sequence (625 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with RMI1?
The strongest Open Targets associations for RMI1 are cancer, lymphocyte count, sex hormone-binding globulin measurement, age at menarche and total blood protein measurement.
How long is the RMI1 protein?
The Homo sapiens RMI1 protein (UniProt Q9H9A7) is 625 amino acids long.
Browse: Targets: R · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H9A7 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H9A7 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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