Spermatogenesis-defective protein 39 homolog (VIPAS39)
Homo sapiens — UniProt Q9H9C1
Data last refreshed: (UniProt release unknown)
Key facts
Spermatogenesis-defective protein 39 homolog (VIPAS39) is a protein from Homo sapiens identified by UniProt accession Q9H9C1, 493 residues long. MolForge cross-references it against 0 known binders and 21 disease associations.
- UniProt accession: Q9H9C1; gene symbol VIPAS39.
- Organism: Homo sapiens.
- Length: 493 amino acids.
- Top disease associations (Open Targets): Arthrogryposis - renal dysfunction - cholestasis, arthrogryposis-renal dysfunction-cholestasis syndrome and arthrogryposis.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Spermatogenesis-defective protein 39 homolog |
|---|---|
| UniProt accession | Q9H9C1 |
| Gene | VIPAS39 |
| Organism | Homo sapiens |
| Length | 493 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (21)
Diseases linked to this target (Open Targets).
- Arthrogryposis - renal dysfunction - cholestasis · score 0.80
- arthrogryposis-renal dysfunction-cholestasis syndrome · score 0.59
- arthrogryposis · score 0.46
- genetic disorder · score 0.19
- leukocyte count · score 0.14
- neutrophil count · score 0.11
- apolipoprotein A 1 measurement · score 0.11
- lymphocyte percentage of leukocytes · score 0.10
- protein measurement · score 0.09
- sum of neutrophil and eosinophil counts · score 0.08
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H9C1-F1 | alphafold | PREDICTED | 78.14 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H9C1.
Amino-acid sequence (493 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with VIPAS39?
The strongest Open Targets associations for VIPAS39 are Arthrogryposis - renal dysfunction - cholestasis, arthrogryposis-renal dysfunction-cholestasis syndrome, arthrogryposis, genetic disorder and leukocyte count.
How long is the VIPAS39 protein?
The Homo sapiens VIPAS39 protein (UniProt Q9H9C1) is 493 amino acids long.
Browse: Targets: V · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H9C1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H9C1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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