Ankyrin repeat family A protein 2 (ANKRA2)
Homo sapiens — UniProt Q9H9E1
Data last refreshed: (UniProt release unknown)
Key facts
Ankyrin repeat family A protein 2 (ANKRA2) is a protein from Homo sapiens identified by UniProt accession Q9H9E1, 313 residues long. MolForge cross-references it against 0 known binders and 35 disease associations.
- UniProt accession: Q9H9E1; gene symbol ANKRA2.
- Organism: Homo sapiens.
- Length: 313 amino acids.
- Top disease associations (Open Targets): lymphocyte count, apolipoprotein A 1 measurement and serum albumin measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Ankyrin repeat family A protein 2 |
|---|---|
| UniProt accession | Q9H9E1 |
| Gene | ANKRA2 |
| Organism | Homo sapiens |
| Length | 313 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (35)
Diseases linked to this target (Open Targets).
- lymphocyte count · score 0.21
- apolipoprotein A 1 measurement · score 0.18
- serum albumin measurement · score 0.17
- protein measurement · score 0.14
- sensorineural hearing loss · score 0.14
- mean platelet volume · score 0.11
- sex hormone-binding globulin measurement · score 0.11
- age-related hearing impairment · score 0.08
- sitting height measurement · score 0.07
- C-reactive protein measurement · score 0.06
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H9E1-F1 | alphafold | PREDICTED | 67.37 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H9E1.
Amino-acid sequence (313 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ANKRA2?
The strongest Open Targets associations for ANKRA2 are lymphocyte count, apolipoprotein A 1 measurement, serum albumin measurement, protein measurement and sensorineural hearing loss.
How long is the ANKRA2 protein?
The Homo sapiens ANKRA2 protein (UniProt Q9H9E1) is 313 amino acids long.
Browse: Targets: A · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H9E1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H9E1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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