Actin-related protein 5 (ACTR5)
Homo sapiens — UniProt Q9H9F9
Data last refreshed: (UniProt release unknown)
Key facts
Actin-related protein 5 (ACTR5) is a protein from Homo sapiens identified by UniProt accession Q9H9F9, 607 residues long. MolForge cross-references it against 0 known binders and 26 disease associations.
- UniProt accession: Q9H9F9; gene symbol ACTR5.
- Organism: Homo sapiens.
- Length: 607 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, depressive symptom measurement and glioblastoma multiforme.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Actin-related protein 5 |
|---|---|
| UniProt accession | Q9H9F9 |
| Gene | ACTR5 |
| Organism | Homo sapiens |
| Length | 607 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (26)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.53
- depressive symptom measurement · score 0.21
- glioblastoma multiforme · score 0.18
- schizophrenia · score 0.18
- anorexia nervosa · score 0.16
- metabolite measurement · score 0.13
- clear cell renal carcinoma · score 0.10
- hepatocellular carcinoma · score 0.07
- age at menarche · score 0.05
- neoplasm · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H9F9-F1 | alphafold | PREDICTED | 82.77 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H9F9.
Amino-acid sequence (607 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ACTR5?
The strongest Open Targets associations for ACTR5 are neurodegenerative disease, depressive symptom measurement, glioblastoma multiforme, schizophrenia and anorexia nervosa.
How long is the ACTR5 protein?
The Homo sapiens ACTR5 protein (UniProt Q9H9F9) is 607 amino acids long.
Browse: Targets: A · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H9F9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H9F9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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