Endogenous retroviral envelope protein HEMO (ERVMER34-1)
Homo sapiens — UniProt Q9H9K5
Data last refreshed: (UniProt release unknown)
Key facts
Endogenous retroviral envelope protein HEMO (ERVMER34-1) is a protein from Homo sapiens identified by UniProt accession Q9H9K5, 563 residues long. MolForge cross-references it against 0 known binders and 41 disease associations.
- UniProt accession: Q9H9K5; gene symbol ERVMER34-1.
- Organism: Homo sapiens.
- Length: 563 amino acids.
- Top disease associations (Open Targets): neoplasm, body mass index and lung carcinoma.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Endogenous retroviral envelope protein HEMO |
|---|---|
| UniProt accession | Q9H9K5 |
| Gene | ERVMER34-1 |
| Organism | Homo sapiens |
| Length | 563 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (41)
Diseases linked to this target (Open Targets).
- neoplasm · score 0.08
- body mass index · score 0.07
- lung carcinoma · score 0.05
- adult onset asthma · score 0.04
- FEV/FVC ratio · score 0.04
- pancreatic adenocarcinoma · score 0.04
- lymphocyte count · score 0.04
- DNA methylation · score 0.04
- gut microbiome measurement · score 0.03
- cortical surface area measurement · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H9K5-F1 | alphafold | PREDICTED | 44.32 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H9K5.
Amino-acid sequence (563 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ERVMER34-1?
The strongest Open Targets associations for ERVMER34-1 are neoplasm, body mass index, lung carcinoma, adult onset asthma and FEV/FVC ratio.
How long is the ERVMER34-1 protein?
The Homo sapiens ERVMER34-1 protein (UniProt Q9H9K5) is 563 amino acids long.
Browse: Targets: E · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H9K5 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H9K5 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.