KAT8 regulatory NSL complex subunit 2 (KANSL2)
Homo sapiens — UniProt Q9H9L4
Data last refreshed: (UniProt release unknown)
Key facts
KAT8 regulatory NSL complex subunit 2 (KANSL2) is a protein from Homo sapiens identified by UniProt accession Q9H9L4, 492 residues long. MolForge cross-references it against 0 known binders and 28 disease associations.
- UniProt accession: Q9H9L4; gene symbol KANSL2.
- Organism: Homo sapiens.
- Length: 492 amino acids.
- Top disease associations (Open Targets): leukocyte count, breast adenocarcinoma and myeloid white cell count.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | KAT8 regulatory NSL complex subunit 2 |
|---|---|
| UniProt accession | Q9H9L4 |
| Gene | KANSL2 |
| Organism | Homo sapiens |
| Length | 492 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (28)
Diseases linked to this target (Open Targets).
- leukocyte count · score 0.25
- breast adenocarcinoma · score 0.22
- myeloid white cell count · score 0.21
- calcium measurement · score 0.21
- lymphocyte count · score 0.19
- sex hormone-binding globulin measurement · score 0.15
- appendicular lean mass · score 0.10
- body height · score 0.09
- glioblastoma multiforme · score 0.05
- pulse pressure measurement · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H9L4-F1 | alphafold | PREDICTED | 65.82 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H9L4.
Amino-acid sequence (492 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with KANSL2?
The strongest Open Targets associations for KANSL2 are leukocyte count, breast adenocarcinoma, myeloid white cell count, calcium measurement and lymphocyte count.
How long is the KANSL2 protein?
The Homo sapiens KANSL2 protein (UniProt Q9H9L4) is 492 amino acids long.
Browse: Targets: K · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H9L4 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H9L4 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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