Akirin-1 (AKIRIN1)
Homo sapiens — UniProt Q9H9L7
Data last refreshed: (UniProt release unknown)
Key facts
Akirin-1 (AKIRIN1) is a protein from Homo sapiens identified by UniProt accession Q9H9L7, 192 residues long. MolForge cross-references it against 0 known binders and 22 disease associations.
- UniProt accession: Q9H9L7; gene symbol AKIRIN1.
- Organism: Homo sapiens.
- Length: 192 amino acids.
- Top disease associations (Open Targets): lymphocyte count, mean corpuscular volume and sex hormone-binding globulin measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Akirin-1 |
|---|---|
| UniProt accession | Q9H9L7 |
| Gene | AKIRIN1 |
| Organism | Homo sapiens |
| Length | 192 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (22)
Diseases linked to this target (Open Targets).
- lymphocyte count · score 0.35
- mean corpuscular volume · score 0.32
- sex hormone-binding globulin measurement · score 0.30
- eosinophil count · score 0.28
- testosterone measurement · score 0.16
- alcohol drinking · score 0.06
- mathematical ability · score 0.05
- Sepsis · score 0.03
- Urinary incontinence · score 0.02
- complication · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H9L7-F1 | alphafold | PREDICTED | 68.09 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H9L7.
Amino-acid sequence (192 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with AKIRIN1?
The strongest Open Targets associations for AKIRIN1 are lymphocyte count, mean corpuscular volume, sex hormone-binding globulin measurement, eosinophil count and testosterone measurement.
How long is the AKIRIN1 protein?
The Homo sapiens AKIRIN1 protein (UniProt Q9H9L7) is 192 amino acids long.
Browse: Targets: A · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H9L7 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H9L7 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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