COP9 signalosome complex subunit 7b (COPS7B)
Homo sapiens — UniProt Q9H9Q2
Data last refreshed: (UniProt release unknown)
Key facts
COP9 signalosome complex subunit 7b (COPS7B) is a protein from Homo sapiens identified by UniProt accession Q9H9Q2, 264 residues long. MolForge cross-references it against 0 known binders and 13 disease associations.
- UniProt accession: Q9H9Q2; gene symbol COPS7B.
- Organism: Homo sapiens.
- Length: 264 amino acids.
- Top disease associations (Open Targets): glioblastoma multiforme, body mass index and Iridocyclitis.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | COP9 signalosome complex subunit 7b |
|---|---|
| UniProt accession | Q9H9Q2 |
| Gene | COPS7B |
| Organism | Homo sapiens |
| Length | 264 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (13)
Diseases linked to this target (Open Targets).
- glioblastoma multiforme · score 0.23
- body mass index · score 0.23
- Iridocyclitis · score 0.19
- lung adenocarcinoma · score 0.18
- breast adenocarcinoma · score 0.18
- erythrocyte count · score 0.11
- renal cell carcinoma · score 0.07
- red blood cell density measurement · score 0.03
- head and neck squamous cell carcinoma · score 0.03
- mean corpuscular hemoglobin · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H9Q2-F1 | alphafold | PREDICTED | 84.76 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H9Q2.
Amino-acid sequence (264 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with COPS7B?
The strongest Open Targets associations for COPS7B are glioblastoma multiforme, body mass index, Iridocyclitis, lung adenocarcinoma and breast adenocarcinoma.
How long is the COPS7B protein?
The Homo sapiens COPS7B protein (UniProt Q9H9Q2) is 264 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H9Q2 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H9Q2 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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