Calcium-binding protein 39-like (CAB39L)
Homo sapiens — UniProt Q9H9S4
Data last refreshed: (UniProt release unknown)
Key facts
Calcium-binding protein 39-like (CAB39L) is a protein from Homo sapiens identified by UniProt accession Q9H9S4, 337 residues long. MolForge cross-references it against 0 known binders and 67 disease associations.
- UniProt accession: Q9H9S4; gene symbol CAB39L.
- Organism: Homo sapiens.
- Length: 337 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, Parkinson disease and exanthem.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Calcium-binding protein 39-like |
|---|---|
| UniProt accession | Q9H9S4 |
| Gene | CAB39L |
| Organism | Homo sapiens |
| Length | 337 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (67)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.36
- Parkinson disease · score 0.29
- exanthem · score 0.28
- alcohol consumption measurement · score 0.28
- pancreatic adenocarcinoma · score 0.28
- PR interval · score 0.28
- lung adenocarcinoma · score 0.27
- mean corpuscular volume · score 0.20
- endometrial cancer · score 0.18
- vital capacity · score 0.14
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H9S4-F1 | alphafold | PREDICTED | 93.81 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H9S4.
Amino-acid sequence (337 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with CAB39L?
The strongest Open Targets associations for CAB39L are neurodegenerative disease, Parkinson disease, exanthem, alcohol consumption measurement and pancreatic adenocarcinoma.
How long is the CAB39L protein?
The Homo sapiens CAB39L protein (UniProt Q9H9S4) is 337 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H9S4 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H9S4 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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