Elongator complex protein 3 (ELP3)
Homo sapiens — UniProt Q9H9T3
Data last refreshed: (UniProt release unknown)
Key facts
Elongator complex protein 3 (ELP3) is a protein from Homo sapiens identified by UniProt accession Q9H9T3, 547 residues long. MolForge cross-references it against 0 known binders and 61 disease associations.
- UniProt accession: Q9H9T3; gene symbol ELP3.
- Organism: Homo sapiens.
- Length: 547 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, body mass index and ulcerative colitis.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Elongator complex protein 3 |
|---|---|
| UniProt accession | Q9H9T3 |
| Gene | ELP3 |
| Organism | Homo sapiens |
| Length | 547 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (61)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.54
- body mass index · score 0.29
- ulcerative colitis · score 0.23
- breast adenocarcinoma · score 0.22
- creatinine measurement · score 0.22
- body height · score 0.22
- familial amyotrophic lateral sclerosis · score 0.18
- sporadic amyotrophic lateral sclerosis · score 0.18
- amyotrophic lateral sclerosis · score 0.12
- neoplasm · score 0.09
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H9T3-F1 | alphafold | PREDICTED | 91.88 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H9T3.
Amino-acid sequence (547 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ELP3?
The strongest Open Targets associations for ELP3 are neurodegenerative disease, body mass index, ulcerative colitis, breast adenocarcinoma and creatinine measurement.
How long is the ELP3 protein?
The Homo sapiens ELP3 protein (UniProt Q9H9T3) is 547 amino acids long.
Browse: Targets: E · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H9T3 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H9T3 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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