RING finger protein 122 (RNF122)
Homo sapiens — UniProt Q9H9V4
Data last refreshed: (UniProt release unknown)
Key facts
RING finger protein 122 (RNF122) is a protein from Homo sapiens identified by UniProt accession Q9H9V4, 155 residues long. MolForge cross-references it against 0 known binders and 22 disease associations.
- UniProt accession: Q9H9V4; gene symbol RNF122.
- Organism: Homo sapiens.
- Length: 155 amino acids.
- Top disease associations (Open Targets): chronotype measurement, body height and pulse pressure measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | RING finger protein 122 |
|---|---|
| UniProt accession | Q9H9V4 |
| Gene | RNF122 |
| Organism | Homo sapiens |
| Length | 155 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (22)
Diseases linked to this target (Open Targets).
- chronotype measurement · score 0.26
- body height · score 0.22
- pulse pressure measurement · score 0.19
- risk-taking behaviour · score 0.17
- alcohol consumption measurement · score 0.15
- response to vaccine · score 0.14
- forced expiratory volume · score 0.13
- protein measurement · score 0.09
- attention deficit hyperactivity disorder · score 0.04
- breast carcinoma · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H9V4-F1 | alphafold | PREDICTED | 71.85 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H9V4.
Amino-acid sequence (155 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with RNF122?
The strongest Open Targets associations for RNF122 are chronotype measurement, body height, pulse pressure measurement, risk-taking behaviour and alcohol consumption measurement.
How long is the RNF122 protein?
The Homo sapiens RNF122 protein (UniProt Q9H9V4) is 155 amino acids long.
Browse: Targets: R · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H9V4 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H9V4 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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