2-oxoglutarate and iron-dependent oxygenase JMJD4 (JMJD4)
Homo sapiens — UniProt Q9H9V9
Data last refreshed: (UniProt release unknown)
Key facts
2-oxoglutarate and iron-dependent oxygenase JMJD4 (JMJD4) is a protein from Homo sapiens identified by UniProt accession Q9H9V9, 417 residues long. MolForge cross-references it against 0 known binders and 32 disease associations.
- UniProt accession: Q9H9V9; gene symbol JMJD4.
- Organism: Homo sapiens.
- Length: 417 amino acids.
- Top disease associations (Open Targets): body height, BMI-adjusted waist-hip ratio and genetic disorder.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | 2-oxoglutarate and iron-dependent oxygenase JMJD4 |
|---|---|
| UniProt accession | Q9H9V9 |
| Gene | JMJD4 |
| Organism | Homo sapiens |
| Length | 417 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (32)
Diseases linked to this target (Open Targets).
- body height · score 0.16
- BMI-adjusted waist-hip ratio · score 0.13
- genetic disorder · score 0.12
- sitting height measurement · score 0.11
- BMI-adjusted waist circumference · score 0.11
- hematocrit · score 0.06
- nonpapillary renal cell carcinoma · score 0.06
- cystatin C measurement · score 0.05
- hemoglobin measurement · score 0.04
- tooth agenesis · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H9V9-F1 | alphafold | PREDICTED | 93.52 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H9V9.
Amino-acid sequence (417 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with JMJD4?
The strongest Open Targets associations for JMJD4 are body height, BMI-adjusted waist-hip ratio, genetic disorder, sitting height measurement and BMI-adjusted waist circumference.
How long is the JMJD4 protein?
The Homo sapiens JMJD4 protein (UniProt Q9H9V9) is 417 amino acids long.
Browse: Targets: J · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H9V9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H9V9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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