Ribosome production factor 1 (RPF1)
Homo sapiens — UniProt Q9H9Y2
Data last refreshed: (UniProt release unknown)
Key facts
Ribosome production factor 1 (RPF1) is a protein from Homo sapiens identified by UniProt accession Q9H9Y2, 349 residues long. MolForge cross-references it against 0 known binders and 13 disease associations.
- UniProt accession: Q9H9Y2; gene symbol RPF1.
- Organism: Homo sapiens.
- Length: 349 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, infection and infect.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Ribosome production factor 1 |
|---|---|
| UniProt accession | Q9H9Y2 |
| Gene | RPF1 |
| Organism | Homo sapiens |
| Length | 349 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (13)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.41
- infection · score 0.01
- infect · score 0.01
- type 2 diabetes mellitus · score 0.00
- skin basal cell carcinoma · score 0.00
- squamous cell carcinoma · score 0.00
- temporal arteritis · score 0.00
- Steinert myotonic dystrophy · score 0.00
- neoplasm · score 0.00
- infertility · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H9Y2-F1 | alphafold | PREDICTED | 84.63 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H9Y2.
Amino-acid sequence (349 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with RPF1?
The strongest Open Targets associations for RPF1 are neurodegenerative disease, infection, infect, type 2 diabetes mellitus and skin basal cell carcinoma.
How long is the RPF1 protein?
The Homo sapiens RPF1 protein (UniProt Q9H9Y2) is 349 amino acids long.
Browse: Targets: R · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H9Y2 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H9Y2 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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