Uridine-cytidine kinase 1 (UCK1)
Homo sapiens — UniProt Q9HA47
Data last refreshed: (UniProt release unknown)
Key facts
Uridine-cytidine kinase 1 (UCK1) is a protein from Homo sapiens identified by UniProt accession Q9HA47, 277 residues long. MolForge cross-references it against 1 known binders and 7 disease associations.
- UniProt accession: Q9HA47; gene symbol UCK1.
- Organism: Homo sapiens.
- Length: 277 amino acids.
- Top disease associations (Open Targets): urate measurement, cutaneous melanoma and fat body mass.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Uridine-cytidine kinase 1 |
|---|---|
| UniProt accession | Q9HA47 |
| Gene | UCK1 |
| Organism | Homo sapiens |
| Length | 277 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (7)
Diseases linked to this target (Open Targets).
- urate measurement · score 0.17
- cutaneous melanoma · score 0.13
- fat body mass · score 0.11
- lean body mass · score 0.07
- appendicular lean mass · score 0.04
- type 2 diabetes mellitus · score 0.02
- acute myeloid leukemia · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9HA47-F1 | alphafold | PREDICTED | 83.53 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9HA47.
Amino-acid sequence (277 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with UCK1?
The strongest Open Targets associations for UCK1 are urate measurement, cutaneous melanoma, fat body mass, lean body mass and appendicular lean mass.
How long is the UCK1 protein?
The Homo sapiens UCK1 protein (UniProt Q9HA47) is 277 amino acids long.
Browse: Targets: U · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9HA47 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9HA47 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.