Succinyl-CoA:glutarate CoA-transferase (SUGCT)
Homo sapiens — UniProt Q9HAC7
Data last refreshed: (UniProt release unknown)
Key facts
Succinyl-CoA:glutarate CoA-transferase (SUGCT) is a protein from Homo sapiens identified by UniProt accession Q9HAC7, 438 residues long. MolForge cross-references it against 0 known binders and 114 disease associations.
- UniProt accession: Q9HAC7; gene symbol SUGCT.
- Organism: Homo sapiens.
- Length: 438 amino acids.
- Top disease associations (Open Targets): glutaric acidemia type 3, pulse pressure measurement and migraine disorder.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Succinyl-CoA:glutarate CoA-transferase |
|---|---|
| UniProt accession | Q9HAC7 |
| Gene | SUGCT |
| Organism | Homo sapiens |
| Length | 438 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (114)
Diseases linked to this target (Open Targets).
- glutaric acidemia type 3 · score 0.62
- pulse pressure measurement · score 0.44
- migraine disorder · score 0.43
- systolic blood pressure · score 0.43
- testosterone measurement · score 0.40
- vital capacity · score 0.40
- prostate carcinoma · score 0.36
- pancreatic carcinoma · score 0.36
- type 2 diabetes mellitus · score 0.36
- acne · score 0.36
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9HAC7-F1 | alphafold | PREDICTED | 91.80 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9HAC7.
Amino-acid sequence (438 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SUGCT?
The strongest Open Targets associations for SUGCT are glutaric acidemia type 3, pulse pressure measurement, migraine disorder, systolic blood pressure and testosterone measurement.
How long is the SUGCT protein?
The Homo sapiens SUGCT protein (UniProt Q9HAC7) is 438 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9HAC7 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9HAC7 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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