Ubiquitin domain-containing protein 1 (UBTD1)
Homo sapiens — UniProt Q9HAC8
Data last refreshed: (UniProt release unknown)
Key facts
Ubiquitin domain-containing protein 1 (UBTD1) is a protein from Homo sapiens identified by UniProt accession Q9HAC8, 227 residues long. MolForge cross-references it against 0 known binders and 27 disease associations.
- UniProt accession: Q9HAC8; gene symbol UBTD1.
- Organism: Homo sapiens.
- Length: 227 amino acids.
- Top disease associations (Open Targets): BMI-adjusted waist circumference, serum gamma-glutamyl transferase measurement and hepatocellular carcinoma.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Ubiquitin domain-containing protein 1 |
|---|---|
| UniProt accession | Q9HAC8 |
| Gene | UBTD1 |
| Organism | Homo sapiens |
| Length | 227 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (27)
Diseases linked to this target (Open Targets).
- BMI-adjusted waist circumference · score 0.08
- serum gamma-glutamyl transferase measurement · score 0.06
- hepatocellular carcinoma · score 0.06
- serum alanine aminotransferase measurement · score 0.04
- granulocyte percentage of myeloid white cells · score 0.04
- cancer · score 0.03
- neutrophil count · score 0.03
- neoplasm · score 0.03
- platelet count · score 0.03
- sex hormone-binding globulin measurement · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9HAC8-F1 | alphafold | PREDICTED | 74.66 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9HAC8.
Amino-acid sequence (227 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with UBTD1?
The strongest Open Targets associations for UBTD1 are BMI-adjusted waist circumference, serum gamma-glutamyl transferase measurement, hepatocellular carcinoma, serum alanine aminotransferase measurement and granulocyte percentage of myeloid white cells.
How long is the UBTD1 protein?
The Homo sapiens UBTD1 protein (UniProt Q9HAC8) is 227 amino acids long.
Browse: Targets: U · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9HAC8 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9HAC8 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.