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WD repeat-containing protein 41 (WDR41)

Homo sapiens — UniProt Q9HAD4

Gene: WDR41Homo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

WD repeat-containing protein 41 (WDR41) is a protein from Homo sapiens identified by UniProt accession Q9HAD4, 459 residues long. MolForge cross-references it against 0 known binders and 64 disease associations.

  • UniProt accession: Q9HAD4; gene symbol WDR41.
  • Organism: Homo sapiens.
  • Length: 459 amino acids.
  • Top disease associations (Open Targets): aspartate aminotransferase measurement, urate measurement and heel bone mineral density.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameWD repeat-containing protein 41
UniProt accessionQ9HAD4
GeneWDR41
OrganismHomo sapiens
Length459 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (64)

Diseases linked to this target (Open Targets).

  • aspartate aminotransferase measurement · score 0.38
  • urate measurement · score 0.36
  • heel bone mineral density · score 0.36
  • FEV/FVC ratio · score 0.34
  • monocyte count · score 0.34
  • vital capacity · score 0.30
  • neurodegenerative disease · score 0.27
  • platelet component distribution width · score 0.09
  • mean platelet volume · score 0.08
  • triple-negative breast cancer · score 0.07

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q9HAD4-F1alphafoldPREDICTED82.33—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9HAD4.

Amino-acid sequence (459 residues)

MLRWLIGGGR EPQGLAEKSP LQTIGEEQTQ NPYTELLVLK AHHDIVRFLV QLDDYRFASA GDDGIVVVWN AQTGEKLLEL NGHTQKITAI ITFPSLESCE EKNQLILTAS ADRTVIVWDG DTTRQVQRIS CFQSTVKCLT VLQRLDVWLS GGNDLCVWNR KLDLLCKTSH LSDTGISALV EIPKNCVVAA VGKELIIFRL VAPTEGSLEW DILEVKRLLD HQDNILSLIN VNDLSFVTGS HVGELIIWDA LDWTMQAYER NFWDPSPQLD TQQEIKLCQK SNDISIHHFT CDEENVFAAV GRGLYVYSLQ MKRVIACQKT AHDSNVLHVA RLPNRQLISC SEDGSVRIWE LREKQQLAAE PVPTGFFNMW GFGRVSKQAS QPVKKQQENA TSCSLELIGD LIGHSSSVEM FLYFEDHGLV TCSADHLIIL WKNGERESGL RSLRLFQKLE ENGDLYLAV

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with WDR41?

The strongest Open Targets associations for WDR41 are aspartate aminotransferase measurement, urate measurement, heel bone mineral density, FEV/FVC ratio and monocyte count.

How long is the WDR41 protein?

The Homo sapiens WDR41 protein (UniProt Q9HAD4) is 459 amino acids long.

Browse: Targets: W · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ9HAD4
GeneWDR41
OrganismHomo sapiens
Length459
Binders0
Diseases64
View on UniProt