Protein lin-7 homolog B (LIN7B)
Homo sapiens — UniProt Q9HAP6
Data last refreshed: (UniProt release unknown)
Key facts
Protein lin-7 homolog B (LIN7B) is a protein from Homo sapiens identified by UniProt accession Q9HAP6, 207 residues long. MolForge cross-references it against 0 known binders and 20 disease associations.
- UniProt accession: Q9HAP6; gene symbol LIN7B.
- Organism: Homo sapiens.
- Length: 207 amino acids.
- Top disease associations (Open Targets): systolic blood pressure, puberty onset measurement and diastolic blood pressure.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Protein lin-7 homolog B |
|---|---|
| UniProt accession | Q9HAP6 |
| Gene | LIN7B |
| Organism | Homo sapiens |
| Length | 207 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (20)
Diseases linked to this target (Open Targets).
- systolic blood pressure · score 0.10
- puberty onset measurement · score 0.10
- diastolic blood pressure · score 0.09
- vital capacity · score 0.08
- lean body mass · score 0.07
- pulse pressure measurement · score 0.07
- mean arterial pressure · score 0.07
- fat body mass · score 0.05
- appendicular lean mass · score 0.05
- hypertension · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9HAP6-F1 | alphafold | PREDICTED | 87.17 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9HAP6.
Amino-acid sequence (207 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with LIN7B?
The strongest Open Targets associations for LIN7B are systolic blood pressure, puberty onset measurement, diastolic blood pressure, vital capacity and lean body mass.
How long is the LIN7B protein?
The Homo sapiens LIN7B protein (UniProt Q9HAP6) is 207 amino acids long.
Browse: Targets: L · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9HAP6 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9HAP6 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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