Ropporin-1A (ROPN1)
Homo sapiens — UniProt Q9HAT0
Data last refreshed: (UniProt release unknown)
Key facts
Ropporin-1A (ROPN1) is a protein from Homo sapiens identified by UniProt accession Q9HAT0, 212 residues long. MolForge cross-references it against 0 known binders and 70 disease associations.
- UniProt accession: Q9HAT0; gene symbol ROPN1.
- Organism: Homo sapiens.
- Length: 212 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, mathematical ability and self reported educational attainment.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Ropporin-1A |
|---|---|
| UniProt accession | Q9HAT0 |
| Gene | ROPN1 |
| Organism | Homo sapiens |
| Length | 212 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (70)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.26
- mathematical ability · score 0.16
- self reported educational attainment · score 0.10
- intelligence · score 0.08
- azoospermia · score 0.07
- male infertility with teratozoospermia due to single gene mutation · score 0.07
- spermatogenic failure 3 · score 0.06
- spermatogenic failure 55 · score 0.06
- spermatogenic failure 7 · score 0.06
- cognitive function measurement · score 0.06
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9HAT0-F1 | alphafold | PREDICTED | 85.22 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9HAT0.
Amino-acid sequence (212 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ROPN1?
The strongest Open Targets associations for ROPN1 are neurodegenerative disease, mathematical ability, self reported educational attainment, intelligence and azoospermia.
How long is the ROPN1 protein?
The Homo sapiens ROPN1 protein (UniProt Q9HAT0) is 212 amino acids long.
Browse: Targets: R · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9HAT0 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9HAT0 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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