Protein ERGIC-53-like (LMAN1L)
Homo sapiens — UniProt Q9HAT1
Data last refreshed: (UniProt release unknown)
Key facts
Protein ERGIC-53-like (LMAN1L) is a protein from Homo sapiens identified by UniProt accession Q9HAT1, 526 residues long. MolForge cross-references it against 0 known binders and 65 disease associations.
- UniProt accession: Q9HAT1; gene symbol LMAN1L.
- Organism: Homo sapiens.
- Length: 526 amino acids.
- Top disease associations (Open Targets): systolic blood pressure, alcohol consumption measurement and mean arterial pressure.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Protein ERGIC-53-like |
|---|---|
| UniProt accession | Q9HAT1 |
| Gene | LMAN1L |
| Organism | Homo sapiens |
| Length | 526 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (65)
Diseases linked to this target (Open Targets).
- systolic blood pressure · score 0.27
- alcohol consumption measurement · score 0.27
- mean arterial pressure · score 0.26
- alcohol drinking · score 0.24
- lymphocyte count · score 0.23
- low density lipoprotein cholesterol measurement · score 0.19
- apolipoprotein B measurement · score 0.18
- blood phosphate measurement · score 0.16
- cutaneous melanoma · score 0.14
- celiac disease · score 0.13
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9HAT1-F1 | alphafold | PREDICTED | 67.99 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9HAT1.
Amino-acid sequence (526 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with LMAN1L?
The strongest Open Targets associations for LMAN1L are systolic blood pressure, alcohol consumption measurement, mean arterial pressure, alcohol drinking and lymphocyte count.
How long is the LMAN1L protein?
The Homo sapiens LMAN1L protein (UniProt Q9HAT1) is 526 amino acids long.
Browse: Targets: L · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9HAT1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9HAT1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.