Claspin (CLSPN)
Homo sapiens — UniProt Q9HAW4
Data last refreshed: (UniProt release unknown)
Key facts
Claspin (CLSPN) is a protein from Homo sapiens identified by UniProt accession Q9HAW4, 1339 residues long. MolForge cross-references it against 0 known binders and 95 disease associations.
- UniProt accession: Q9HAW4; gene symbol CLSPN.
- Organism: Homo sapiens.
- Length: 1339 amino acids.
- Top disease associations (Open Targets): mean corpuscular volume, mean corpuscular hemoglobin and mean reticulocyte volume.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Claspin |
|---|---|
| UniProt accession | Q9HAW4 |
| Gene | CLSPN |
| Organism | Homo sapiens |
| Length | 1339 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (95)
Diseases linked to this target (Open Targets).
- mean corpuscular volume · score 0.55
- mean corpuscular hemoglobin · score 0.32
- mean reticulocyte volume · score 0.31
- breast adenocarcinoma · score 0.28
- ovarian cancer · score 0.28
- glioblastoma multiforme · score 0.28
- endometrial cancer · score 0.26
- lung adenocarcinoma · score 0.25
- esophageal cancer · score 0.19
- hematological measurement · score 0.17
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9HAW4-F1 | alphafold | PREDICTED | 50.63 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9HAW4.
Amino-acid sequence (1339 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with CLSPN?
The strongest Open Targets associations for CLSPN are mean corpuscular volume, mean corpuscular hemoglobin, mean reticulocyte volume, breast adenocarcinoma and ovarian cancer.
How long is the CLSPN protein?
The Homo sapiens CLSPN protein (UniProt Q9HAW4) is 1339 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9HAW4 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9HAW4 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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