Melanoma-associated antigen F1 (MAGEF1)
Homo sapiens — UniProt Q9HAY2
Data last refreshed: (UniProt release unknown)
Key facts
Melanoma-associated antigen F1 (MAGEF1) is a protein from Homo sapiens identified by UniProt accession Q9HAY2, 307 residues long. MolForge cross-references it against 0 known binders and 14 disease associations.
- UniProt accession: Q9HAY2; gene symbol MAGEF1.
- Organism: Homo sapiens.
- Length: 307 amino acids.
- Top disease associations (Open Targets): vital capacity, heel bone mineral density and balding measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Melanoma-associated antigen F1 |
|---|---|
| UniProt accession | Q9HAY2 |
| Gene | MAGEF1 |
| Organism | Homo sapiens |
| Length | 307 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (14)
Diseases linked to this target (Open Targets).
- vital capacity · score 0.27
- heel bone mineral density · score 0.26
- balding measurement · score 0.24
- facial morphology measurement · score 0.23
- lower face morphology measurement · score 0.12
- nose morphology measurement · score 0.08
- acute myeloid leukemia · score 0.00
- metastatic melanoma · score 0.00
- neoplasm · score 0.00
- hepatocellular carcinoma · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9HAY2-F1 | alphafold | PREDICTED | 80.20 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9HAY2.
Amino-acid sequence (307 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with MAGEF1?
The strongest Open Targets associations for MAGEF1 are vital capacity, heel bone mineral density, balding measurement, facial morphology measurement and lower face morphology measurement.
How long is the MAGEF1 protein?
The Homo sapiens MAGEF1 protein (UniProt Q9HAY2) is 307 amino acids long.
Browse: Targets: M · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9HAY2 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9HAY2 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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