Cadherin-related family member 5 (CDHR5)
Homo sapiens — UniProt Q9HBB8
Data last refreshed: (UniProt release unknown)
Key facts
Cadherin-related family member 5 (CDHR5) is a protein from Homo sapiens identified by UniProt accession Q9HBB8, 845 residues long. MolForge cross-references it against 0 known binders and 49 disease associations.
- UniProt accession: Q9HBB8; gene symbol CDHR5.
- Organism: Homo sapiens.
- Length: 845 amino acids.
- Top disease associations (Open Targets): systemic lupus erythematosus, systemic scleroderma and hypothyroidism.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Cadherin-related family member 5 |
|---|---|
| UniProt accession | Q9HBB8 |
| Gene | CDHR5 |
| Organism | Homo sapiens |
| Length | 845 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (49)
Diseases linked to this target (Open Targets).
- systemic lupus erythematosus · score 0.23
- systemic scleroderma · score 0.18
- hypothyroidism · score 0.15
- myxedema · score 0.11
- rheumatoid arthritis · score 0.08
- myositis · score 0.08
- high density lipoprotein cholesterol measurement · score 0.08
- Autosomal dominant polycystic kidney disease · score 0.08
- Barrett's esophagus · score 0.07
- neoplasm · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9HBB8-F1 | alphafold | PREDICTED | 68.31 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9HBB8.
Amino-acid sequence (845 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with CDHR5?
The strongest Open Targets associations for CDHR5 are systemic lupus erythematosus, systemic scleroderma, hypothyroidism, myxedema and rheumatoid arthritis.
How long is the CDHR5 protein?
The Homo sapiens CDHR5 protein (UniProt Q9HBB8) is 845 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9HBB8 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9HBB8 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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