Roquin-2 (RC3H2)
Homo sapiens — UniProt Q9HBD1
Data last refreshed: (UniProt release unknown)
Key facts
Roquin-2 (RC3H2) is a protein from Homo sapiens identified by UniProt accession Q9HBD1, 1191 residues long. MolForge cross-references it against 0 known binders and 48 disease associations.
- UniProt accession: Q9HBD1; gene symbol RC3H2.
- Organism: Homo sapiens.
- Length: 1191 amino acids.
- Top disease associations (Open Targets): type 2 diabetes mellitus, lymphocyte percentage of leukocytes and behavior.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Roquin-2 |
|---|---|
| UniProt accession | Q9HBD1 |
| Gene | RC3H2 |
| Organism | Homo sapiens |
| Length | 1191 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (48)
Diseases linked to this target (Open Targets).
- type 2 diabetes mellitus · score 0.13
- lymphocyte percentage of leukocytes · score 0.10
- behavior · score 0.10
- enthesopathy · score 0.10
- insomnia measurement · score 0.09
- wellbeing measurement · score 0.09
- oral squamous cell carcinoma · score 0.07
- cholesterol-ester transfer protein deficiency · score 0.05
- birth weight · score 0.05
- hypertriglyceridemia 2 · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9HBD1-F1 | alphafold | PREDICTED | 56.13 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9HBD1.
Amino-acid sequence (1191 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with RC3H2?
The strongest Open Targets associations for RC3H2 are type 2 diabetes mellitus, lymphocyte percentage of leukocytes, behavior, enthesopathy and insomnia measurement.
How long is the RC3H2 protein?
The Homo sapiens RC3H2 protein (UniProt Q9HBD1) is 1191 amino acids long.
Browse: Targets: R · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9HBD1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9HBD1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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