Beta-parvin (PARVB)
Homo sapiens — UniProt Q9HBI1
Data last refreshed: (UniProt release unknown)
Key facts
Beta-parvin (PARVB) is a protein from Homo sapiens identified by UniProt accession Q9HBI1, 364 residues long. MolForge cross-references it against 0 known binders and 79 disease associations.
- UniProt accession: Q9HBI1; gene symbol PARVB.
- Organism: Homo sapiens.
- Length: 364 amino acids.
- Top disease associations (Open Targets): monocyte count, serum gamma-glutamyl transferase measurement and Red cell distribution width.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Beta-parvin |
|---|---|
| UniProt accession | Q9HBI1 |
| Gene | PARVB |
| Organism | Homo sapiens |
| Length | 364 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (79)
Diseases linked to this target (Open Targets).
- monocyte count · score 0.40
- serum gamma-glutamyl transferase measurement · score 0.33
- Red cell distribution width · score 0.32
- parental longevity · score 0.21
- traffic air pollution measurement · score 0.21
- asthma · score 0.21
- non-alcoholic fatty liver disease · score 0.20
- type 2 diabetes mellitus · score 0.14
- head and neck squamous cell carcinoma · score 0.10
- triglyceride measurement · score 0.09
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9HBI1-F1 | alphafold | PREDICTED | 81.77 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9HBI1.
Amino-acid sequence (364 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with PARVB?
The strongest Open Targets associations for PARVB are monocyte count, serum gamma-glutamyl transferase measurement, Red cell distribution width, parental longevity and traffic air pollution measurement.
How long is the PARVB protein?
The Homo sapiens PARVB protein (UniProt Q9HBI1) is 364 amino acids long.
Browse: Targets: P · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9HBI1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9HBI1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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