Centrosomal protein 15 (CEP15)
Homo sapiens — UniProt Q9HBI5
Data last refreshed: (UniProt release unknown)
Key facts
Centrosomal protein 15 (CEP15) is a protein from Homo sapiens identified by UniProt accession Q9HBI5, 128 residues long. MolForge cross-references it against 0 known binders and 83 disease associations.
- UniProt accession: Q9HBI5; gene symbol CEP15.
- Organism: Homo sapiens.
- Length: 128 amino acids.
- Top disease associations (Open Targets): body height, body mass index and Blackfan-Diamond anemia.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Centrosomal protein 15 |
|---|---|
| UniProt accession | Q9HBI5 |
| Gene | CEP15 |
| Organism | Homo sapiens |
| Length | 128 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (83)
Diseases linked to this target (Open Targets).
- body height · score 0.12
- body mass index · score 0.09
- Blackfan-Diamond anemia · score 0.09
- self reported educational attainment · score 0.08
- alpha thalassemia-intellectual disability syndrome type 1 · score 0.07
- Alpha-thalassemia - intellectual disability syndrome linked to chromosome 16 · score 0.07
- mathematical ability · score 0.06
- cortical surface area measurement · score 0.06
- hemolytic anemia due to adenylate kinase deficiency · score 0.06
- Heinz body anemia · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9HBI5-F1 | alphafold | PREDICTED | 86.22 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9HBI5.
Amino-acid sequence (128 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with CEP15?
The strongest Open Targets associations for CEP15 are body height, body mass index, Blackfan-Diamond anemia, self reported educational attainment and alpha thalassemia-intellectual disability syndrome type 1.
How long is the CEP15 protein?
The Homo sapiens CEP15 protein (UniProt Q9HBI5) is 128 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9HBI5 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9HBI5 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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