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Cytochrome P450 4F11 (CYP4F11)

Homo sapiens — UniProt Q9HBI6

Gene: CYP4F11Homo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

Cytochrome P450 4F11 (CYP4F11) is a protein from Homo sapiens identified by UniProt accession Q9HBI6, 524 residues long. MolForge cross-references it against 0 known binders and 231 disease associations.

  • UniProt accession: Q9HBI6; gene symbol CYP4F11.
  • Organism: Homo sapiens.
  • Length: 524 amino acids.
  • Top disease associations (Open Targets): cutaneous melanoma, glioblastoma multiforme and heel bone mineral density.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameCytochrome P450 4F11
UniProt accessionQ9HBI6
GeneCYP4F11
OrganismHomo sapiens
Length524 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (231)

Diseases linked to this target (Open Targets).

  • cutaneous melanoma · score 0.26
  • glioblastoma multiforme · score 0.23
  • heel bone mineral density · score 0.21
  • lung adenocarcinoma · score 0.18
  • endometrial cancer · score 0.18
  • urinary metabolite measurement · score 0.11
  • serum metabolite measurement · score 0.10
  • response to anticoagulant · score 0.09
  • aspartate aminotransferase measurement · score 0.08
  • neoplasm · score 0.08

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q9HBI6-F1alphafoldPREDICTED91.62—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9HBI6.

Amino-acid sequence (524 residues)

MPQLSLSWLG LGPVAASPWL LLLLVGGSWL LARVLAWTYT FYDNCRRLQC FPQPPKQNWF WGHQGLVTPT EEGMKTLTQL VTTYPQGFKL WLGPTFPLLI LCHPDIIRPI TSASAAVAPK DMIFYGFLKP WLGDGLLLSG GDKWSRHRRM LTPAFHFNIL KPYMKIFNKS VNIMHDKWQR LASEGSARLD MFEHISLMTL DSLQKCVFSF ESNCQEKPSE YIAAILELSA FVEKRNQQIL LHTDFLYYLT PDGQRFRRAC HLVHDFTDAV IQERRCTLPT QGIDDFLKNK AKSKTLDFID VLLLSKDEDG KELSDEDIRA EADTFMFEGH DTTASGLSWV LYHLAKHPEY QEQCRQEVQE LLKDREPIEI EWDDLAQLPF LTMCIKESLR LHPPVPVISR CCTQDFVLPD GRVIPKGIVC LINIIGIHYN PTVWPDPEVY DPFRFDQENI KERSPLAFIP FSAGPRNCIG QAFAMAEMKV VLALTLLHFR ILPTHTEPRR KPELILRAEG GLWLRVEPLG ANSQ

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with CYP4F11?

The strongest Open Targets associations for CYP4F11 are cutaneous melanoma, glioblastoma multiforme, heel bone mineral density, lung adenocarcinoma and endometrial cancer.

How long is the CYP4F11 protein?

The Homo sapiens CYP4F11 protein (UniProt Q9HBI6) is 524 amino acids long.

Browse: Targets: C · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ9HBI6
GeneCYP4F11
OrganismHomo sapiens
Length524
Binders0
Diseases231
View on UniProt