Plasminogen receptor (KT) (PLGRKT)
Homo sapiens — UniProt Q9HBL7
Data last refreshed: (UniProt release unknown)
Key facts
Plasminogen receptor (KT) (PLGRKT) is a protein from Homo sapiens identified by UniProt accession Q9HBL7, 147 residues long. MolForge cross-references it against 0 known binders and 58 disease associations.
- UniProt accession: Q9HBL7; gene symbol PLGRKT.
- Organism: Homo sapiens.
- Length: 147 amino acids.
- Top disease associations (Open Targets): Thyroid preparation use measurement, hypothyroidism and myxedema.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Plasminogen receptor (KT) |
|---|---|
| UniProt accession | Q9HBL7 |
| Gene | PLGRKT |
| Organism | Homo sapiens |
| Length | 147 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (58)
Diseases linked to this target (Open Targets).
- Thyroid preparation use measurement · score 0.38
- hypothyroidism · score 0.33
- myxedema · score 0.26
- thyroid disease · score 0.26
- autoimmune thyroid disease · score 0.23
- drug use measurement · score 0.23
- polycystic ovary syndrome · score 0.19
- Chronic mucocutaneous candidosis · score 0.09
- acne inversa, familial, 3 · score 0.08
- platelet crit · score 0.06
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9HBL7-F1 | alphafold | PREDICTED | 89.69 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9HBL7.
Amino-acid sequence (147 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with PLGRKT?
The strongest Open Targets associations for PLGRKT are Thyroid preparation use measurement, hypothyroidism, myxedema, thyroid disease and autoimmune thyroid disease.
How long is the PLGRKT protein?
The Homo sapiens PLGRKT protein (UniProt Q9HBL7) is 147 amino acids long.
Browse: Targets: P · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9HBL7 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9HBL7 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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