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Vezatin (VEZT)

Homo sapiens — UniProt Q9HBM0

Gene: VEZTHomo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

Vezatin (VEZT) is a protein from Homo sapiens identified by UniProt accession Q9HBM0, 779 residues long. MolForge cross-references it against 0 known binders and 48 disease associations.

  • UniProt accession: Q9HBM0; gene symbol VEZT.
  • Organism: Homo sapiens.
  • Length: 779 amino acids.
  • Top disease associations (Open Targets): neurodegenerative disease, endometriosis and uterine disorder.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameVezatin
UniProt accessionQ9HBM0
GeneVEZT
OrganismHomo sapiens
Length779 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (48)

Diseases linked to this target (Open Targets).

  • neurodegenerative disease · score 0.54
  • endometriosis · score 0.28
  • uterine disorder · score 0.19
  • Ovarian Endometriosis · score 0.18
  • high density lipoprotein cholesterol measurement · score 0.18
  • sleep duration · score 0.18
  • wet macular degeneration · score 0.13
  • aspirin use measurement · score 0.11
  • platelet component distribution width · score 0.09
  • FEV/FVC ratio · score 0.07

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q9HBM0-F1alphafoldPREDICTED65.45—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9HBM0.

Amino-acid sequence (779 residues)

MTPEFDEEVV FENSPLYQYL QDLGHTDFEI CSSLSPKTEK CTTEGQQKPP TRVLPKQGIL LKVAETIKSW IFFSQCNKKD DLLHKLDIGF RLDSLHTILQ QEVLLQEDVE LIELLDPSIL SAGQSQQQEN GHLPTLCSLA TPNIWDLSML FAFISLLVML PTWWIVSSWL VWGVILFVYL VIRALRLWRT AKLQVTLKKY SVHLEDMATN SRAFTNLVRK ALRLIQETEV ISRGFTLVSA ACPFNKAGQH PSQHLIGLRK AVYRTLRANF QAARLATLYM LKNYPLNSES DNVTNYICVV PFKELGLGLS EEQISEEEAH NFTDGFSLPA LKVLFQLWVA QSSEFFRRLA LLLSTANSPP GPLLTPALLP HRILSDVTQG LPHAHSACLE ELKRSYEFYR YFETQHQSVP QCLSKTQQKS RELNNVHTAV RSLQLHLKAL LNEVIILEDE LEKLVCTKET QELVSEAYPI LEQKLKLIQP HVQASNNCWE EAISQVDKLL RRNTDKKGKP EIACENPHCT VVPLKQPTLH IADKDPIPEE QELEAYVDDI DIDSDFRKDD FYYLSQEDKE RQKREHEESK RVLQELKSVL GFKASEAERQ KWKQLLFSDH AVLKSLSPVD PVEPISNSEP SMNSDMGKVS KNDTEEESNK SATTDNEISR TEYLCENSLE GKNKDNSSNE VFPQGAEERM CYQCESEDEP QADGSGLTTA PPTPRDSLQP SIKQRLARLQ LSPDFTFTAG LAAEVAARSL SFTTMQEQTF GGEEEEQIIE ENKNEIEEK

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with VEZT?

The strongest Open Targets associations for VEZT are neurodegenerative disease, endometriosis, uterine disorder, Ovarian Endometriosis and high density lipoprotein cholesterol measurement.

How long is the VEZT protein?

The Homo sapiens VEZT protein (UniProt Q9HBM0) is 779 amino acids long.

Browse: Targets: V · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ9HBM0
GeneVEZT
OrganismHomo sapiens
Length779
Binders0
Diseases48
View on UniProt