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Transcription initiation factor TFIID subunit 9B (TAF9B)

Homo sapiens — UniProt Q9HBM6

Gene: TAF9BHomo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

Transcription initiation factor TFIID subunit 9B (TAF9B) is a protein from Homo sapiens identified by UniProt accession Q9HBM6, 251 residues long. MolForge cross-references it against 0 known binders and 19 disease associations.

  • UniProt accession: Q9HBM6; gene symbol TAF9B.
  • Organism: Homo sapiens.
  • Length: 251 amino acids.
  • Top disease associations (Open Targets): HIV infection, low grade glioma and head and neck squamous cell carcinoma.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameTranscription initiation factor TFIID subunit 9B
UniProt accessionQ9HBM6
GeneTAF9B
OrganismHomo sapiens
Length251 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (19)

Diseases linked to this target (Open Targets).

  • HIV infection · score 0.58
  • low grade glioma · score 0.27
  • head and neck squamous cell carcinoma · score 0.18
  • lung adenocarcinoma · score 0.18
  • endometrial cancer · score 0.18
  • small cell lung carcinoma · score 0.14
  • Intellectual disability · score 0.11
  • osteosarcoma · score 0.07
  • Graves disease · score 0.05
  • dilated cardiomyopathy 1I · score 0.03

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q9HBM6-F1alphafoldPREDICTED66.58—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9HBM6.

Amino-acid sequence (251 residues)

MESGKMAPPK NAPRDALVMA QILKDMGITE YEPRVINQML EFAFRYVTTI LDDAKIYSSH AKKPNVDADD VRLAIQCRAD QSFTSPPPRD FLLDIARQKN QTPLPLIKPY AGPRLPPDRY CLTAPNYRLK SLIKKGPNQG RLVPRLSVGA VSSKPTTPTI ATPQTVSVPN KVATPMSVTS QRFTVQIPPS QSTPVKPVPA TTAVQNVLIN PSMIGPKNIL ITTNMVSSQN TANEANPLKR KHEDDDDNDI M

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with TAF9B?

The strongest Open Targets associations for TAF9B are HIV infection, low grade glioma, head and neck squamous cell carcinoma, lung adenocarcinoma and endometrial cancer.

How long is the TAF9B protein?

The Homo sapiens TAF9B protein (UniProt Q9HBM6) is 251 amino acids long.

Browse: Targets: T · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ9HBM6
GeneTAF9B
OrganismHomo sapiens
Length251
Binders0
Diseases19
View on UniProt