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Cadherin-20 (CDH20)

Homo sapiens — UniProt Q9HBT6

Gene: CDH20Homo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

Cadherin-20 (CDH20) is a protein from Homo sapiens identified by UniProt accession Q9HBT6, 801 residues long. MolForge cross-references it against 0 known binders and 35 disease associations.

  • UniProt accession: Q9HBT6; gene symbol CDH20.
  • Organism: Homo sapiens.
  • Length: 801 amino acids.
  • Top disease associations (Open Targets): self reported educational attainment, neurofibrillary tangles measurement and visual perception measurement.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameCadherin-20
UniProt accessionQ9HBT6
GeneCDH20
OrganismHomo sapiens
Length801 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (35)

Diseases linked to this target (Open Targets).

  • self reported educational attainment · score 0.40
  • neurofibrillary tangles measurement · score 0.33
  • visual perception measurement · score 0.32
  • diet measurement · score 0.30
  • handedness · score 0.25
  • serum urea measurement · score 0.21
  • glomerular filtration rate · score 0.15
  • drug use measurement · score 0.14
  • creatinine measurement · score 0.13
  • metabolite measurement · score 0.12

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q9HBT6-F1alphafoldPREDICTED77.29—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9HBT6.

Amino-acid sequence (801 residues)

MWTSGRMSNA KNWLGLGMSL YFWGLMDLTT TVLSDTPTPQ GELEALLSDK PQSHQRTKRS WVWNQFFVLE EYTGTDPLYV GKLHSDMDRG DGSIKYILSG EGAGIVFTID DTTGDIHAIQ RLDREERAQY TLRAQALDRR TGRPMEPESE FIIKIQDIND NEPKFLDGPY VATVPEMSPV GTSVIQVTAT DADDPTYGNS ARVVYSILQG QPYFSVDSKT GVIRTALMNM DREAKEYYEV IIQAKDMGGQ LGGLAGTTTV NITLSDVNDN PPRFPQKHYQ MSVLESAPIS STVGRVFAKD LDEGINAEMK YTIVDGDGAD AFDISTDPNF QVGIITVKKP LSFESKKSYT LKVEGANPHL EMRFLNLGPF QDTTTVHISV EDVDEPPVFE PGFYFVEVPE DVAIGTTIQI ISAKDPDVTN NSIRYSIDRS SDPGRFFYVD ITTGALMTAR PLDREEFSWH NITVLAMEMN NPSQVGSVPV TIKVLDVNDN APEFPRFYEA FVCENAKAGQ LIQTVSAVDQ DDPRNGQHFY YSLAPEAANN PNFTIRDNQD NTARILTRRS GFRQQEQSVF HLPILIADSG QPVLSSTGTL TIQVCSCDDD GHVMSCSPEA YMLPVSLSRG ALIAILACIF VLLVLVLLIL SMRRHRKQPY IIDDEENIHE NIVRYDDEGG GEEDTEAFDI AAMWNPREAQ AGAAPKTRQD MLPEIESLSR YVPQTCAVNS TVHSYVLAKL YEADMDLWAP PFDSLQTYMF EGDGSVAGSL SSLQSATSDS EQSFDFLTDW GPRFRKLAEL YGASEGPAPL W

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with CDH20?

The strongest Open Targets associations for CDH20 are self reported educational attainment, neurofibrillary tangles measurement, visual perception measurement, diet measurement and handedness.

How long is the CDH20 protein?

The Homo sapiens CDH20 protein (UniProt Q9HBT6) is 801 amino acids long.

Browse: Targets: C · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ9HBT6
GeneCDH20
OrganismHomo sapiens
Length801
Binders0
Diseases35
View on UniProt