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Zinc finger protein 287 (ZNF287)

Homo sapiens — UniProt Q9HBT7

Gene: ZNF287Homo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

Zinc finger protein 287 (ZNF287) is a protein from Homo sapiens identified by UniProt accession Q9HBT7, 761 residues long. MolForge cross-references it against 0 known binders and 8 disease associations.

  • UniProt accession: Q9HBT7; gene symbol ZNF287.
  • Organism: Homo sapiens.
  • Length: 761 amino acids.
  • Top disease associations (Open Targets): prostate cancer, prostate carcinoma and Familial prostate cancer.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameZinc finger protein 287
UniProt accessionQ9HBT7
GeneZNF287
OrganismHomo sapiens
Length761 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (8)

Diseases linked to this target (Open Targets).

  • prostate cancer · score 0.11
  • prostate carcinoma · score 0.11
  • Familial prostate cancer · score 0.11
  • Benign familial chorea · score 0.07
  • Ataxia - oculomotor apraxia type 1 · score 0.05
  • early-onset generalized limb-onset dystonia · score 0.05
  • neoplasm · score 0.01
  • bladder transitional cell carcinoma · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q9HBT7-F1alphafoldPREDICTED68.20—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9HBT7.

Amino-acid sequence (761 residues)

MLASSKRMNS SSRSQILLRW KSDKAQSGPY NVEKEILTSR FLRDTETCRQ NFRNFPYPDL AGPRKALSQL RELCLKWLRP EIHSKEQILE LLVLEQFLTI LPGEVRTWVK SQYPESSEEA VTLVEDLTQI LEEEAPQNST LSQDTPEEDP RGKHAFQTGW LNDLVTKESM TFKDVAVDIT QEDWELMRPV QKELYKTVTL QNYWNMVSLG LTVYRPTVIP ILEEPWMVIK EILEGPSPEW ETKAQACTPV EDMSKLTKEE THTIKLEDSY DYDDRLERRG KGGFWKIHTD ERGFSLKSVL SQEYDPTEEC LSKYDIYRNN FEKHSNLIVQ FDTQLDNKTS VYNEGRATFN HVSYGIVHRK ILPGEKPYKC NVCGKKFRKY PSLLKHQSTH AKEKSYECEE CGKEFRHISS LIAHQRMHTG EKPYECHQCG KAFSQRAHLT IHQRIHTGEK PYKCDDCGKD FSQRAHLTIH QRTHTGEKPY KCLECGKTFS HSSSLINHQR VHTGEKPYIC NECGKTFSQS THLLQHQKIH TGKKPYKCNE CWKVFSQSTY LIRHQRIHSG EKCYKCNECG KAFAHSSTLI QHQTTHTGEK SYICNICGKA FSQSANLTQH HRTHTGEKPY KCSVCGKAFS QSVHLTQHQR IHNGEKPFKC NICGKAYRQG ANLTQHQRIH TGEKPYKCNE CGKAFIYSSS LNQHQRTHTG ERPYKCNECD KDFSQRTCLI QHQRIHTGEK PYACRICGKT FTQSTNLIQH QRVHTGAKHR N

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with ZNF287?

The strongest Open Targets associations for ZNF287 are prostate cancer, prostate carcinoma, Familial prostate cancer, Benign familial chorea and Ataxia - oculomotor apraxia type 1.

How long is the ZNF287 protein?

The Homo sapiens ZNF287 protein (UniProt Q9HBT7) is 761 amino acids long.

Browse: Targets: Z · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ9HBT7
GeneZNF287
OrganismHomo sapiens
Length761
Binders0
Diseases8
View on UniProt