Ethanolamine kinase 1 (ETNK1)
Homo sapiens — UniProt Q9HBU6
Data last refreshed: (UniProt release unknown)
Key facts
Ethanolamine kinase 1 (ETNK1) is a protein from Homo sapiens identified by UniProt accession Q9HBU6, 452 residues long. MolForge cross-references it against 0 known binders and 163 disease associations.
- UniProt accession: Q9HBU6; gene symbol ETNK1.
- Organism: Homo sapiens.
- Length: 452 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, wellbeing measurement and chronic myelogenous leukemia.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Ethanolamine kinase 1 |
|---|---|
| UniProt accession | Q9HBU6 |
| Gene | ETNK1 |
| Organism | Homo sapiens |
| Length | 452 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (163)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.54
- wellbeing measurement · score 0.39
- chronic myelogenous leukemia · score 0.37
- Endometrial Endometrioid Adenocarcinoma · score 0.37
- bile duct carcinoma · score 0.37
- lymphoid neoplasm · score 0.37
- esophageal adenocarcinoma · score 0.37
- breast ductal adenocarcinoma · score 0.37
- Hepatobiliary Neoplasm · score 0.37
- Ovarian Endometrioid Adenocarcinoma with Squamous Differentiation · score 0.37
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9HBU6-F1 | alphafold | PREDICTED | 83.76 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9HBU6.
Amino-acid sequence (452 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ETNK1?
The strongest Open Targets associations for ETNK1 are neurodegenerative disease, wellbeing measurement, chronic myelogenous leukemia, Endometrial Endometrioid Adenocarcinoma and bile duct carcinoma.
How long is the ETNK1 protein?
The Homo sapiens ETNK1 protein (UniProt Q9HBU6) is 452 amino acids long.
Browse: Targets: E · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9HBU6 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9HBU6 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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