NADPH oxidase 3 (NOX3)
Homo sapiens — UniProt Q9HBY0
Data last refreshed: (UniProt release unknown)
Key facts
NADPH oxidase 3 (NOX3) is a protein from Homo sapiens identified by UniProt accession Q9HBY0, 568 residues long. MolForge cross-references it against 0 known binders and 111 disease associations.
- UniProt accession: Q9HBY0; gene symbol NOX3.
- Organism: Homo sapiens.
- Length: 568 amino acids.
- Top disease associations (Open Targets): diet measurement, self reported educational attainment and mathematical ability.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | NADPH oxidase 3 |
|---|---|
| UniProt accession | Q9HBY0 |
| Gene | NOX3 |
| Organism | Homo sapiens |
| Length | 568 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (111)
Diseases linked to this target (Open Targets).
- diet measurement · score 0.41
- self reported educational attainment · score 0.31
- mathematical ability · score 0.29
- body mass index · score 0.26
- cognitive function measurement · score 0.22
- sunburn · score 0.21
- body height · score 0.21
- intelligence · score 0.18
- schizophrenia · score 0.18
- PHF-tau measurement · score 0.18
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9HBY0-F1 | alphafold | PREDICTED | 89.70 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9HBY0.
Amino-acid sequence (568 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with NOX3?
The strongest Open Targets associations for NOX3 are diet measurement, self reported educational attainment, mathematical ability, body mass index and cognitive function measurement.
How long is the NOX3 protein?
The Homo sapiens NOX3 protein (UniProt Q9HBY0) is 568 amino acids long.
Browse: Targets: N · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9HBY0 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9HBY0 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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