Glycerophosphoinositol inositolphosphodiesterase GDPD2 (GDPD2)
Homo sapiens — UniProt Q9HCC8
Data last refreshed: (UniProt release unknown)
Key facts
Glycerophosphoinositol inositolphosphodiesterase GDPD2 (GDPD2) is a protein from Homo sapiens identified by UniProt accession Q9HCC8, 539 residues long. MolForge cross-references it against 0 known binders and 24 disease associations.
- UniProt accession: Q9HCC8; gene symbol GDPD2.
- Organism: Homo sapiens.
- Length: 539 amino acids.
- Top disease associations (Open Targets): MODY, hyperproinsulinemia and Barrett's esophagus.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Glycerophosphoinositol inositolphosphodiesterase GDPD2 |
|---|---|
| UniProt accession | Q9HCC8 |
| Gene | GDPD2 |
| Organism | Homo sapiens |
| Length | 539 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (24)
Diseases linked to this target (Open Targets).
- MODY · score 0.07
- hyperproinsulinemia · score 0.05
- Barrett's esophagus · score 0.05
- Glycogen storage disease due to hepatic glycogen synthase deficiency · score 0.04
- glycogen storage disorder due to hepatic glycogen synthase deficiency · score 0.04
- breast carcinoma · score 0.04
- diabetes mellitus, permanent neonatal 4 · score 0.03
- diabetes mellitus, transient neonatal, 3 · score 0.03
- transient neonatal diabetes mellitus · score 0.03
- colorectal adenocarcinoma · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9HCC8-F1 | alphafold | PREDICTED | 90.39 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9HCC8.
Amino-acid sequence (539 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with GDPD2?
The strongest Open Targets associations for GDPD2 are MODY, hyperproinsulinemia, Barrett's esophagus, Glycogen storage disease due to hepatic glycogen synthase deficiency and glycogen storage disorder due to hepatic glycogen synthase deficiency.
How long is the GDPD2 protein?
The Homo sapiens GDPD2 protein (UniProt Q9HCC8) is 539 amino acids long.
Browse: Targets: G · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9HCC8 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9HCC8 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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