Helicase MOV-10 (MOV10)
Homo sapiens — UniProt Q9HCE1
Data last refreshed: (UniProt release unknown)
Key facts
Helicase MOV-10 (MOV10) is a protein from Homo sapiens identified by UniProt accession Q9HCE1, 1003 residues long. MolForge cross-references it against 0 known binders and 117 disease associations.
- UniProt accession: Q9HCE1; gene symbol MOV10.
- Organism: Homo sapiens.
- Length: 1003 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, cancer and body height.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Helicase MOV-10 |
|---|---|
| UniProt accession | Q9HCE1 |
| Gene | MOV10 |
| Organism | Homo sapiens |
| Length | 1003 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (117)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.52
- cancer · score 0.46
- body height · score 0.36
- sex hormone-binding globulin measurement · score 0.32
- platelet count · score 0.32
- intraocular pressure measurement · score 0.31
- cortical surface area measurement · score 0.31
- aspartate aminotransferase measurement · score 0.30
- monocyte count · score 0.30
- glioblastoma multiforme · score 0.29
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9HCE1-F1 | alphafold | PREDICTED | 81.08 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9HCE1.
Amino-acid sequence (1003 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with MOV10?
The strongest Open Targets associations for MOV10 are neurodegenerative disease, cancer, body height, sex hormone-binding globulin measurement and platelet count.
How long is the MOV10 protein?
The Homo sapiens MOV10 protein (UniProt Q9HCE1) is 1003 amino acids long.
Browse: Targets: M · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9HCE1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9HCE1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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