Zinc finger protein 532 (ZNF532)
Homo sapiens — UniProt Q9HCE3
Data last refreshed: (UniProt release unknown)
Key facts
Zinc finger protein 532 (ZNF532) is a protein from Homo sapiens identified by UniProt accession Q9HCE3, 1301 residues long. MolForge cross-references it against 0 known binders and 95 disease associations.
- UniProt accession: Q9HCE3; gene symbol ZNF532.
- Organism: Homo sapiens.
- Length: 1301 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, neurofibrillary tangles measurement and PHF-tau measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Zinc finger protein 532 |
|---|---|
| UniProt accession | Q9HCE3 |
| Gene | ZNF532 |
| Organism | Homo sapiens |
| Length | 1301 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (95)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.51
- neurofibrillary tangles measurement · score 0.21
- PHF-tau measurement · score 0.21
- prostate carcinoma · score 0.12
- obesity · score 0.12
- autism · score 0.12
- percutaneous transluminal coronary angioplasty · score 0.09
- dehydrated hereditary stomatocytosis · score 0.05
- hemoglobin E-beta-thalassemia syndrome · score 0.05
- Rh deficiency syndrome · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9HCE3-F1 | alphafold | PREDICTED | 52.83 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9HCE3.
Amino-acid sequence (1301 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ZNF532?
The strongest Open Targets associations for ZNF532 are neurodegenerative disease, neurofibrillary tangles measurement, PHF-tau measurement, prostate carcinoma and obesity.
How long is the ZNF532 protein?
The Homo sapiens ZNF532 protein (UniProt Q9HCE3) is 1301 amino acids long.
Browse: Targets: Z · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9HCE3 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9HCE3 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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