Anoctamin-8 (ANO8)
Homo sapiens — UniProt Q9HCE9
Data last refreshed: (UniProt release unknown)
Key facts
Anoctamin-8 (ANO8) is a protein from Homo sapiens identified by UniProt accession Q9HCE9, 1232 residues long. MolForge cross-references it against 0 known binders and 35 disease associations.
- UniProt accession: Q9HCE9; gene symbol ANO8.
- Organism: Homo sapiens.
- Length: 1232 amino acids.
- Top disease associations (Open Targets): COVID-19, neurodegenerative disease and breast adenocarcinoma.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Anoctamin-8 |
|---|---|
| UniProt accession | Q9HCE9 |
| Gene | ANO8 |
| Organism | Homo sapiens |
| Length | 1232 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (35)
Diseases linked to this target (Open Targets).
- COVID-19 · score 0.37
- neurodegenerative disease · score 0.26
- breast adenocarcinoma · score 0.16
- mitochondrial DNA measurement · score 0.13
- Abnormality of refraction · score 0.06
- attention deficit hyperactivity disorder · score 0.06
- total cholesterol measurement · score 0.05
- hypertriglyceridemia 2 · score 0.05
- Tourette syndrome · score 0.05
- cholesterol-ester transfer protein deficiency · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9HCE9-F1 | alphafold | PREDICTED | 62.09 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9HCE9.
Amino-acid sequence (1232 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ANO8?
The strongest Open Targets associations for ANO8 are COVID-19, neurodegenerative disease, breast adenocarcinoma, mitochondrial DNA measurement and Abnormality of refraction.
How long is the ANO8 protein?
The Homo sapiens ANO8 protein (UniProt Q9HCE9) is 1232 amino acids long.
Browse: Targets: A · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9HCE9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9HCE9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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