Nck-associated protein 5-like (NCKAP5L)
Homo sapiens — UniProt Q9HCH0
Data last refreshed: (UniProt release unknown)
Key facts
Nck-associated protein 5-like (NCKAP5L) is a protein from Homo sapiens identified by UniProt accession Q9HCH0, 1334 residues long. MolForge cross-references it against 0 known binders and 44 disease associations.
- UniProt accession: Q9HCH0; gene symbol NCKAP5L.
- Organism: Homo sapiens.
- Length: 1334 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, obesity and metabolic syndrome.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Nck-associated protein 5-like |
|---|---|
| UniProt accession | Q9HCH0 |
| Gene | NCKAP5L |
| Organism | Homo sapiens |
| Length | 1334 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (44)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.54
- obesity · score 0.19
- metabolic syndrome · score 0.09
- age at menarche · score 0.09
- alcohol consumption measurement · score 0.08
- waist circumference · score 0.08
- body mass index · score 0.08
- cancer · score 0.07
- neoplasm · score 0.07
- smoking behavior · score 0.06
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9HCH0-F1 | alphafold | PREDICTED | 46.80 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9HCH0.
Amino-acid sequence (1334 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with NCKAP5L?
The strongest Open Targets associations for NCKAP5L are neurodegenerative disease, obesity, metabolic syndrome, age at menarche and alcohol consumption measurement.
How long is the NCKAP5L protein?
The Homo sapiens NCKAP5L protein (UniProt Q9HCH0) is 1334 amino acids long.
Browse: Targets: N · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9HCH0 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9HCH0 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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