Copine-5 (CPNE5)
Homo sapiens — UniProt Q9HCH3
Data last refreshed: (UniProt release unknown)
Key facts
Copine-5 (CPNE5) is a protein from Homo sapiens identified by UniProt accession Q9HCH3, 593 residues long. MolForge cross-references it against 0 known binders and 41 disease associations.
- UniProt accession: Q9HCH3; gene symbol CPNE5.
- Organism: Homo sapiens.
- Length: 593 amino acids.
- Top disease associations (Open Targets): heart rate variability measurement, metabolite measurement and systemic lupus erythematosus.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Copine-5 |
|---|---|
| UniProt accession | Q9HCH3 |
| Gene | CPNE5 |
| Organism | Homo sapiens |
| Length | 593 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (41)
Diseases linked to this target (Open Targets).
- heart rate variability measurement · score 0.17
- metabolite measurement · score 0.17
- systemic lupus erythematosus · score 0.17
- basophil percentage of leukocytes · score 0.13
- diet measurement · score 0.12
- unipolar depression · score 0.09
- resting heart rate · score 0.07
- major depressive disorder · score 0.07
- obsessive-compulsive disorder · score 0.06
- heart rate response to exercise · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9HCH3-F1 | alphafold | PREDICTED | 84.93 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9HCH3.
Amino-acid sequence (593 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with CPNE5?
The strongest Open Targets associations for CPNE5 are heart rate variability measurement, metabolite measurement, systemic lupus erythematosus, basophil percentage of leukocytes and diet measurement.
How long is the CPNE5 protein?
The Homo sapiens CPNE5 protein (UniProt Q9HCH3) is 593 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9HCH3 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9HCH3 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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