Synaptotagmin-like protein 2 (SYTL2)
Homo sapiens — UniProt Q9HCH5
Data last refreshed: (UniProt release unknown)
Key facts
Synaptotagmin-like protein 2 (SYTL2) is a protein from Homo sapiens identified by UniProt accession Q9HCH5, 934 residues long. MolForge cross-references it against 0 known binders and 79 disease associations.
- UniProt accession: Q9HCH5; gene symbol SYTL2.
- Organism: Homo sapiens.
- Length: 934 amino acids.
- Top disease associations (Open Targets): body height, age at first sexual intercourse measurement and angioedema.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Synaptotagmin-like protein 2 |
|---|---|
| UniProt accession | Q9HCH5 |
| Gene | SYTL2 |
| Organism | Homo sapiens |
| Length | 934 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (79)
Diseases linked to this target (Open Targets).
- body height · score 0.41
- age at first sexual intercourse measurement · score 0.12
- angioedema · score 0.11
- sitting height measurement · score 0.09
- lean body mass · score 0.09
- Barrett's esophagus · score 0.06
- waist-hip ratio · score 0.06
- mean corpuscular volume · score 0.05
- gut microbiome measurement · score 0.05
- mean corpuscular hemoglobin concentration · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9HCH5-F1 | alphafold | PREDICTED | 57.72 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9HCH5.
Amino-acid sequence (934 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SYTL2?
The strongest Open Targets associations for SYTL2 are body height, age at first sexual intercourse measurement, angioedema, sitting height measurement and lean body mass.
How long is the SYTL2 protein?
The Homo sapiens SYTL2 protein (UniProt Q9HCH5) is 934 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9HCH5 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9HCH5 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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