Zinc finger protein 14 homolog (ZFP14)
Homo sapiens — UniProt Q9HCL3
Data last refreshed: (UniProt release unknown)
Key facts
Zinc finger protein 14 homolog (ZFP14) is a protein from Homo sapiens identified by UniProt accession Q9HCL3, 533 residues long. MolForge cross-references it against 0 known binders and 54 disease associations.
- UniProt accession: Q9HCL3; gene symbol ZFP14.
- Organism: Homo sapiens.
- Length: 533 amino acids.
- Top disease associations (Open Targets): monocyte count, neoplasm and cancer.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Zinc finger protein 14 homolog |
|---|---|
| UniProt accession | Q9HCL3 |
| Gene | ZFP14 |
| Organism | Homo sapiens |
| Length | 533 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (54)
Diseases linked to this target (Open Targets).
- monocyte count · score 0.15
- neoplasm · score 0.08
- cancer · score 0.07
- vital capacity · score 0.07
- Generalized epilepsy with febrile seizures-plus · score 0.07
- generalised epilepsy · score 0.07
- juvenile myoclonic epilepsy · score 0.06
- Benign familial neonatal seizures · score 0.06
- Febrile seizure (within the age range of 3 months to 6 years) · score 0.06
- temporal lobe epilepsy · score 0.06
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9HCL3-F1 | alphafold | PREDICTED | 71.13 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9HCL3.
Amino-acid sequence (533 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ZFP14?
The strongest Open Targets associations for ZFP14 are monocyte count, neoplasm, cancer, vital capacity and Generalized epilepsy with febrile seizures-plus.
How long is the ZFP14 protein?
The Homo sapiens ZFP14 protein (UniProt Q9HCL3) is 533 amino acids long.
Browse: Targets: Z · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9HCL3 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9HCL3 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.