Casein kinase I isoform gamma-1 (CSNK1G1)
Homo sapiens — UniProt Q9HCP0
Data last refreshed: (UniProt release unknown)
Key facts
Casein kinase I isoform gamma-1 (CSNK1G1) is a protein from Homo sapiens identified by UniProt accession Q9HCP0, 422 residues long. MolForge cross-references it against 3 known binders and 67 disease associations.
- UniProt accession: Q9HCP0; gene symbol CSNK1G1.
- Organism: Homo sapiens.
- Length: 422 amino acids.
- Top disease associations (Open Targets): Global developmental delay, Abnormality of the face and autism.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Casein kinase I isoform gamma-1 |
|---|---|
| UniProt accession | Q9HCP0 |
| Gene | CSNK1G1 |
| Organism | Homo sapiens |
| Length | 422 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (67)
Diseases linked to this target (Open Targets).
- Global developmental delay · score 0.37
- Abnormality of the face · score 0.37
- autism · score 0.37
- Seizure · score 0.37
- Intellectual disability · score 0.37
- Autism · score 0.37
- Abnormality of limbs · score 0.37
- monocyte count · score 0.34
- mean corpuscular volume · score 0.29
- leukocyte count · score 0.25
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9HCP0-F1 | alphafold | PREDICTED | 78.48 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9HCP0.
Amino-acid sequence (422 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with CSNK1G1?
The strongest Open Targets associations for CSNK1G1 are Global developmental delay, Abnormality of the face, autism, Seizure and Intellectual disability.
How long is the CSNK1G1 protein?
The Homo sapiens CSNK1G1 protein (UniProt Q9HCP0) is 422 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9HCP0 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9HCP0 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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