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Protein-cysteine N-palmitoyltransferase HHAT-like protein (HHATL)

Homo sapiens — UniProt Q9HCP6

Gene: HHATLHomo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

Protein-cysteine N-palmitoyltransferase HHAT-like protein (HHATL) is a protein from Homo sapiens identified by UniProt accession Q9HCP6, 504 residues long. MolForge cross-references it against 0 known binders and 29 disease associations.

  • UniProt accession: Q9HCP6; gene symbol HHATL.
  • Organism: Homo sapiens.
  • Length: 504 amino acids.
  • Top disease associations (Open Targets): body fat distribution, eosinophil count and medulloblastoma.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameProtein-cysteine N-palmitoyltransferase HHAT-like protein
UniProt accessionQ9HCP6
GeneHHATL
OrganismHomo sapiens
Length504 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (29)

Diseases linked to this target (Open Targets).

  • body fat distribution · score 0.07
  • eosinophil count · score 0.03
  • medulloblastoma · score 0.03
  • atypical teratoid rhabdoid tumor · score 0.03
  • astrocytoma · score 0.03
  • glioblastoma multiforme · score 0.02
  • psoriasis · score 0.02
  • cardiac hypertrophy · score 0.02
  • skin squamous cell carcinoma · score 0.01
  • type 2 diabetes mellitus · score 0.01

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q9HCP6-F1alphafoldPREDICTED91.10—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9HCP6.

Amino-acid sequence (504 residues)

MGIKTALPAA ELGLYSLVLS GALAYAGRGL LEASQDGAHR KAFRESVRPG WEYIGRKMDV ADFEWVMWFT SFRNVIIFAL SGHVLFAKLC TMVAPKLRSW MYAVYGALAV MGTMGPWYLL LLLGHCVGLY VASLLGQPWL CLGLGLASLA SFKMDPLISW QSGFVTGTFD LQEVLFHGGS SFTVLRCTSF ALESCAHPDR HYSLADLLKY NFYLPFFFFG PIMTFDRFHA QVSQVEPVRR EGELWHIRAQ AGLSVVAIMA VDIFFHFFYI LTIPSDLKFA NRLPDSALAG LAYSNLVYDW VKAAVLFGVV NTVACLDHLD PPQPPKCITA LYVFAETHFD RGINDWLCKY VYNHIGGEHS AVIPELAATV ATFAITTLWL GPCDIVYLWS FLNCFGLNFE LWMQKLAEWG PLARIEASLS VQMSRRVRAL FGAMNFWAII MYNLVSLNSL KFTELVARRL LLTGFPQTTL SILFVTYCGV QLVKERERTL ALEEEQKQDK EKPE

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with HHATL?

The strongest Open Targets associations for HHATL are body fat distribution, eosinophil count, medulloblastoma, atypical teratoid rhabdoid tumor and astrocytoma.

How long is the HHATL protein?

The Homo sapiens HHATL protein (UniProt Q9HCP6) is 504 amino acids long.

Browse: Targets: H · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ9HCP6
GeneHHATL
OrganismHomo sapiens
Length504
Binders0
Diseases29
View on UniProt