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Polypeptide N-acetylgalactosaminyltransferase 9 (GALNT9)

Homo sapiens — UniProt Q9HCQ5

Gene: GALNT9Homo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

Polypeptide N-acetylgalactosaminyltransferase 9 (GALNT9) is a protein from Homo sapiens identified by UniProt accession Q9HCQ5, 603 residues long. MolForge cross-references it against 0 known binders and 81 disease associations.

  • UniProt accession: Q9HCQ5; gene symbol GALNT9.
  • Organism: Homo sapiens.
  • Length: 603 amino acids.
  • Top disease associations (Open Targets): neurodegenerative disease, body mass index and glioblastoma multiforme.
  • 3D structure: AlphaFold model available.

Target properties

Protein namePolypeptide N-acetylgalactosaminyltransferase 9
UniProt accessionQ9HCQ5
GeneGALNT9
OrganismHomo sapiens
Length603 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (81)

Diseases linked to this target (Open Targets).

  • neurodegenerative disease · score 0.35
  • body mass index · score 0.25
  • glioblastoma multiforme · score 0.14
  • X-linked corneal dermoid · score 0.08
  • X-linked endothelial corneal dystrophy · score 0.08
  • Fuchs endothelial corneal dystrophy · score 0.08
  • autosomal dominant keratitis · score 0.07
  • Lisch epithelial corneal dystrophy · score 0.07
  • Schnyder corneal dystrophy · score 0.07
  • Central cloudy dystrophy of Francois · score 0.07

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q9HCQ5-F1alphafoldPREDICTED89.03—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9HCQ5.

Amino-acid sequence (603 residues)

MAVARKIRTL LTVNILVFVG IVLFSVYCRL QGRSQELVRI VSGDRRVRSR HAKVGTLGDR EAILQRLDHL EEVVYNQLNG LAKPIGLVEG PGGLGQGGLA ATLRDDGQEA EGKYEEYGYN AQLSDRISLD RSIPDYRPRK CRQMSYAQDL PQVSVVFIFV NEALSVILRS VHSVVNHTPS QLLKEVILVD DNSDNVELKF NLDQYVNKRY PGLVKIVRNS RREGLIRARL QGWKAATAPV VGFFDAHVEF NTGWAEPALS RIREDRRRIV LPAIDNIKYS TFEVQQYANA AHGYNWGLRC MYIIPPQDWL DRGDESAPIR TPAMIGCSFV VDREYFGDIG LLDPGMEVYG GENVELGMRV WQCGGSMEVL PCSRVAHIER TRKPYNNDID YYAKRNALRA AEVWMDDFKS HVYMAWNIPM SNPGVDFGDV SERLALRQRL KCRSFKWYLE NVYPEMRVYN NTLTYGEVRN SKASAYCLDQ GAEDGDRAIL YPCHGMSSQL VRYSADGLLQ LGPLGSTAFL PDSKCLVDDG TGRMPTLKKC EDVARPTQRL WDFTQSGPIV SRATGRCLEV EMSKDANFGL RLVVQRCSGQ KWMIRNWIKH ARH

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with GALNT9?

The strongest Open Targets associations for GALNT9 are neurodegenerative disease, body mass index, glioblastoma multiforme, X-linked corneal dermoid and X-linked endothelial corneal dystrophy.

How long is the GALNT9 protein?

The Homo sapiens GALNT9 protein (UniProt Q9HCQ5) is 603 amino acids long.

Browse: Targets: G · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ9HCQ5
GeneGALNT9
OrganismHomo sapiens
Length603
Binders0
Diseases81
View on UniProt