CD209 antigen (CD209)
Homo sapiens — UniProt Q9NNX6
Data last refreshed: (UniProt release unknown)
Key facts
CD209 antigen (CD209) is a protein from Homo sapiens identified by UniProt accession Q9NNX6, 404 residues long. MolForge cross-references it against 0 known binders and 558 disease associations.
- UniProt accession: Q9NNX6; gene symbol CD209.
- Organism: Homo sapiens.
- Length: 404 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, tuberculosis and HIV-1 infection.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | CD209 antigen |
|---|---|
| UniProt accession | Q9NNX6 |
| Gene | CD209 |
| Organism | Homo sapiens |
| Length | 404 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (558)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.37
- tuberculosis · score 0.27
- HIV-1 infection · score 0.24
- lung adenocarcinoma · score 0.23
- hepatocellular carcinoma · score 0.23
- thyroid gland adenocarcinoma · score 0.22
- cutaneous melanoma · score 0.22
- squamous cell lung carcinoma · score 0.22
- gastric adenocarcinoma · score 0.22
- melanoma · score 0.19
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NNX6-F1 | alphafold | PREDICTED | 71.45 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NNX6.
Amino-acid sequence (404 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with CD209?
The strongest Open Targets associations for CD209 are neurodegenerative disease, tuberculosis, HIV-1 infection, lung adenocarcinoma and hepatocellular carcinoma.
How long is the CD209 protein?
The Homo sapiens CD209 protein (UniProt Q9NNX6) is 404 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NNX6 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NNX6 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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