Variable charge X-linked protein 3 (VCX3A)
Homo sapiens — UniProt Q9NNX9
Data last refreshed: (UniProt release unknown)
Key facts
Variable charge X-linked protein 3 (VCX3A) is a protein from Homo sapiens identified by UniProt accession Q9NNX9, 186 residues long. MolForge cross-references it against 0 known binders and 22 disease associations.
- UniProt accession: Q9NNX9; gene symbol VCX3A.
- Organism: Homo sapiens.
- Length: 186 amino acids.
- Top disease associations (Open Targets): genetic disorder, Crohn's disease and schizophrenia.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Variable charge X-linked protein 3 |
|---|---|
| UniProt accession | Q9NNX9 |
| Gene | VCX3A |
| Organism | Homo sapiens |
| Length | 186 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (22)
Diseases linked to this target (Open Targets).
- genetic disorder · score 0.12
- Crohn's disease · score 0.09
- schizophrenia · score 0.03
- dehydroepiandrosterone sulphate measurement · score 0.03
- recessive X-linked ichthyosis · score 0.02
- Intellectual disability · score 0.01
- miotic rate · score 0.01
- ichthyosis · score 0.00
- small cell osteogenic sarcoma · score 0.00
- cancer · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NNX9-F1 | alphafold | PREDICTED | 55.65 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NNX9.
Amino-acid sequence (186 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with VCX3A?
The strongest Open Targets associations for VCX3A are genetic disorder, Crohn's disease, schizophrenia, dehydroepiandrosterone sulphate measurement and recessive X-linked ichthyosis.
How long is the VCX3A protein?
The Homo sapiens VCX3A protein (UniProt Q9NNX9) is 186 amino acids long.
Browse: Targets: V · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NNX9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NNX9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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